{"created":"2023-06-20T15:53:19.144708+00:00","id":143,"links":{},"metadata":{"_buckets":{"deposit":"134164fd-25db-4201-a907-3d030f44b4dc"},"_deposit":{"created_by":2,"id":"143","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"143"},"status":"published"},"_oai":{"id":"oai:fukui-hsu.repo.nii.ac.jp:00000143","sets":["24:36"]},"author_link":["321","319","320"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-06-30","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"19","bibliographicPageStart":"17","bibliographicVolumeNumber":"3","bibliographic_titles":[{"bibliographic_title":"新田塚医療福祉センター雑誌"},{"bibliographic_title":"Journal of  Nittazuka Medical Welfare Center","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"関節リウマチ(以下RA)治療薬リウマトレックスカプセル(以下RTX)とそのジェネリック医薬品メトレート錠について、対象患者のカルテ調査により、その臨床効果を薬剤切り替え前後で比較検討した。その結果、RTXからメトレート錠への切り替え後のC反応性蛋白(以下CRP)、赤血球沈降速度(以下ESR)値に有意な上昇が認められ、その一要因として両剤の薬物体内動態の違いが影響しているのではないかと考えた。今後の課題として、長期使用時における更なる検討と、当院のジェネリック医薬品切り替え時に薬物体内動態も一指標にしていくことがあげられる。","subitem_description_type":"Abstract"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.57502/00000131","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"福井医療大学"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13492519","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"福島, 政江"}],"nameIdentifiers":[{"nameIdentifier":"319","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"水上, 峰宏"}],"nameIdentifiers":[{"nameIdentifier":"320","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"杉本, 和則"}],"nameIdentifiers":[{"nameIdentifier":"321","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-12-15"}],"displaytype":"detail","filename":"2006-4.pdf","filesize":[{"value":"2.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2006-4.pdf","url":"https://fukui-hsu.repo.nii.ac.jp/record/143/files/2006-4.pdf"},"version_id":"4cffc40e-b317-42d8-b272-baf7394ade56"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"RA患者に対するリウマトレックスカプセルとそのジェネリック","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"RA患者に対するリウマトレックスカプセルとそのジェネリック"}]},"item_type_id":"10001","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-06-30"},"publish_date":"2006-06-30","publish_status":"0","recid":"143","relation_version_is_last":true,"title":["RA患者に対するリウマトレックスカプセルとそのジェネリック"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2023-06-20T15:56:51.984279+00:00"}